Genetic diagnosis of hereditary cancer has become possible by identification of germ-line mutations in corresponding genes.
This allows to arrange meaningful diagnostic & preventive interventions for germ-line mutation carriers.
Hereditary cancer syndromes compose a group of genetic defects which delivers highly significant elevation of cancer risk. PCR is used to detect certain changes in gene or chromosome which will help in finding & diagnosing a genetic condition or disease such as cancer. PCR is widely used technique in molecular diagnostics. PCR (Polymerase Chain Reaction) allows the pieces of DNA to be amplified for detection. Molecular testing is used for checking certain changes in gene or chromosome which helps in increasing a person’s risk of developing cancer or other disease, it may also done with other procedures like biopsies to help in diagnosing some types of cancer. Cancers are caused by germ-line mutations which requires significant modification of treatment strategy. Mutation analysis is routinely utilized for diagnosis of hereditary cancer syndromes. There are multiple applications of molecular diagnostics in oncology. Molecular diagnostics is a part of laboratory medicine. 16, 2023 (GLOBE NEWSWIRE) - Molecular Oncology is the integrated basic science program which is composed of diverse group of investigators with strength in cancer stem cells, tumor host interactions, DNA damage repair & genomic instability and other fundamental areas of cancer biology.
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